Structural pathways for macromolecular and cellular transport all through the blood-brain barrier all through inflammatory circumstances. Analysis.
- This evaluation presents an abstract of the highlights of important concepts involving the anatomical routes for the transport of macromolecules and the transmigration of cellular elements all through the blood-brain barrier (BBB) all through irritation. The precise focus will embrace inflammatory leukocytes, neoplastic cells and pathogenic microorganisms along with explicit styles of viruses, micro organism and yeasts.
Anti-Tetanus Toxoid IgG (anti-TT IgG) ELISA Kit
- The experimental animal fashions launched proper right here have been employed effectively by the authors in a number of neutral experiments all through the earlier twenty-five years for investigations of pathologic alterations of the BBB after a variety of experimentally induced accidents and inflammatory circumstances in mammalian and non-mammalian animal species.
Human Junctional Adhesion Molecule 2/JAM-B AssayLite Antibody (PerCP Conjugate)
- The preliminary descriptions of endothelial cell (EC) vesicles or caveolae serving as mini-transporters of fluid substances mainly served as a springboard for lots of subsequent discoveries all through the earlier half century related to mechanisms of uptake of provides into ECs and whether or not or not or not pinocytosis is alleged to the transport of these provides all through EC obstacles beneath common physiologic circumstances and after tissue injury.
Tumor Necrosis Factor Receptor Superfamily Member 5 (CD40) Antibody
- Inside the mid-1970’s, the authors of this evaluation independently utilized morphologic strategies (transmission electron microscopy-TEM), along with the plant protein tracer horseradish peroxidase (HRP) to research macromolecular transport buildings that elevated after the thoughts and spinal twine had been subjected to a variety of accidents.
![]() Survivin antibody |
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70R-36666 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit Polyclonal Survivin antibody |
![]() SURVIVIN antibody |
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70R-21713 | Fitzgerald | 50 ul | EUR 435 |
Description: Rabbit polyclonal SURVIVIN antibody |
![]() Survivin antibody |
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70R-SR006 | Fitzgerald | 100 ug | EUR 327 |
Description: Affinity purified Rabbit polyclonal Survivin antibody |
![]() Survivin Antibody |
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48663-100ul | SAB | 100ul | EUR 333 |
![]() Survivin Antibody |
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48663-50ul | SAB | 50ul | EUR 239 |
![]() Survivin Antibody |
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48710-100ul | SAB | 100ul | EUR 333 |
![]() Survivin Antibody |
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48710-50ul | SAB | 50ul | EUR 239 |
![]() Survivin Antibody |
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3160-100 | Biovision | EUR 316 |
![]() Survivin Antibody |
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3160-30T | Biovision | EUR 146 |
![]() Survivin Antibody |
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3161-100 | Biovision | EUR 338 |
![]() Survivin Antibody |
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3170-100 | Biovision | EUR 316 |
![]() Survivin Antibody |
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3170-30T | Biovision | EUR 146 |
![]() Survivin antibody |
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10R-2082 | Fitzgerald | 100 ul | EUR 403 |
Description: Mouse monoclonal Survivin antibody |
![]() Survivin Antibody |
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24092-100ul | SAB | 100ul | EUR 390 |
![]() Survivin Antibody |
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24093-100ul | SAB | 100ul | EUR 390 |
![]() Survivin Antibody |
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24094-100ul | SAB | 100ul | EUR 390 |
![]() Survivin antibody |
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70R-14013 | Fitzgerald | 100 ug | EUR 322 |
Description: Affinity purified Rabbit polyclonal Survivin antibody |
![]() Survivin antibody |
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70R-11659 | Fitzgerald | 100 ug | EUR 403 |
Description: Rabbit polyclonal Survivin antibody |
![]() Survivin antibody |
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70R-11660 | Fitzgerald | 100 ug | EUR 447 |
Description: Rabbit polyclonal Survivin antibody |
![]() Survivin antibody |
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70R-11668 | Fitzgerald | 100 ug | EUR 403 |
Description: Rabbit polyclonal Survivin antibody |
![]() SURVIVIN antibody |
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PAab098261 | Lifescience Market | 100 ug | EUR 386 |
![]() SURVIVIN antibody |
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PAab09909 | Lifescience Market | 100 ug | EUR 386 |
![]() Survivin |
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RA19022 | Neuromics | 100 ug | EUR 344 |
![]() Polyclonal Survivin Antibody |
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APR00391G | Leading Biology | 0.1mg | EUR 484 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Survivin . This antibody is tested and proven to work in the following applications: |
![]() Polyclonal Survivin Antibody |
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APR00392G | Leading Biology | 0.1mg | EUR 484 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Survivin . This antibody is tested and proven to work in the following applications: |
![]() Polyclonal Survivin Antibody |
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APR06261G | Leading Biology | 0.1 mg | EUR 659 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Survivin . This antibody is tested and proven to work in the following applications: |
![]() Polyclonal Survivin Antibody |
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APR06262G | Leading Biology | 0.1 mg | EUR 659 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Survivin . This antibody is tested and proven to work in the following applications: |
![]() Polyclonal Survivin Antibody |
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APR06263G | Leading Biology | 0.1 mg | EUR 659 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Survivin . This antibody is tested and proven to work in the following applications: |
![]() Polyclonal Survivin Antibody |
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APR13599G | Leading Biology | 0.1mg | EUR 484 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Survivin . This antibody is tested and proven to work in the following applications: |
![]() Survivin Polyclonal Antibody |
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EA179-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against Survivin from Human/ Rat/ Mouse. This antibody is tested and validated for IHC |
![]() Survivin Polyclonal Antibody |
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EA179-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against Survivin from Human/ Rat/ Mouse. This antibody is tested and validated for IHC |
![]() anti- SURVIVIN antibody |
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FNab098261 | FN Test | 100µg | EUR 548.75 |
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Description: Antibody raised against SURVIVIN |
![]() anti- SURVIVIN antibody |
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FNab09909 | FN Test | 100µg | EUR 548.75 |
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Description: Antibody raised against SURVIVIN |
![]() Survivin Polyclonal Antibody |
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ES5790-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against Survivin from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA |
![]() Survivin Polyclonal Antibody |
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ES5790-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against Survivin from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA |
![]() Survivin Polyclonal Antibody |
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ES5791-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against Survivin from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
![]() Survivin Polyclonal Antibody |
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ES5791-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against Survivin from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
![]() Survivin Polyclonal Antibody |
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ES8208-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Rabbit Polyclonal antibody against Survivin from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() Survivin Polyclonal Antibody |
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ES8208-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Rabbit Polyclonal antibody against Survivin from Human/Mouse/Rat. This antibody is tested and validated for IHC |
![]() Survivin Monoclonal Antibody |
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EM1184-100ul | ELK Biotech | 100ul | EUR 279 |
Description: A Mouse Monoclonal antibody against Survivin from Human/ Rat. This antibody is tested and validated for WB, ELISA, IHC |
![]() Survivin Monoclonal Antibody |
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EM1184-50ul | ELK Biotech | 50ul | EUR 207 |
Description: A Mouse Monoclonal antibody against Survivin from Human/ Rat. This antibody is tested and validated for WB, ELISA, IHC |
![]() Survivin (BIRC5) Antibody |
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20-abx125300 | Abbexa |
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![]() Survivin (BIRC5) Antibody |
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20-abx111181 | Abbexa |
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![]() Survivin (Surv) Antibody |
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20-abx129576 | Abbexa |
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![]() Survivin (BIRC5) Antibody |
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20-abx109262 | Abbexa |
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![]() Survivin Polyclonal Antibody |
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ABP57209-003ml | Abbkine | 0.03ml | EUR 158 |
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Description: A polyclonal antibody for detection of Survivin from Human, Mouse, Rat. This Survivin antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein |
![]() Survivin Polyclonal Antibody |
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ABP57209-01ml | Abbkine | 0.1ml | EUR 289 |
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Description: A polyclonal antibody for detection of Survivin from Human, Mouse, Rat. This Survivin antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein |
![]() Survivin Polyclonal Antibody |
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ABP57209-02ml | Abbkine | 0.2ml | EUR 414 |
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Description: A polyclonal antibody for detection of Survivin from Human, Mouse, Rat. This Survivin antibody is for IHC-P. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen recombinant protein |
![]() Survivin Polyclonal Antibody |
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ABP-PAB-10283 | Allele Biotech | 100 ug | Ask for price |
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![]() Survivin (BIRC5) Antibody |
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20-abx001305 | Abbexa |
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![]() Survivin (BIRC5) Antibody |
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20-abx133868 | Abbexa |
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![]() Survivin (BIRC5) Antibody |
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abx038170-100ug | Abbexa | 100 ug | EUR 391 |
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![]() Survivin (Surv) Antibody |
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20-abx100295 | Abbexa |
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![]() Survivin (Surv) Antibody |
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20-abx100296 | Abbexa |
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![]() Survivin (BIRC5) Antibody |
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abx010443-100ul | Abbexa | 100 ul | EUR 411 |
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![]() Survivin (pT117) Antibody |
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abx011575-100ug | Abbexa | 100 ug | EUR 439 |
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![]() Survivin (BIRC5) Antibody |
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20-abx011576 | Abbexa |
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![]() Survivin (BIRC5) Antibody |
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abx011577-100ug | Abbexa | 100 ug | EUR 411 |
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![]() Survivin Polyclonal Antibody |
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ABP54791-003ml | Abbkine | 0.03ml | EUR 158 |
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Description: A polyclonal antibody for detection of Survivin from Human, Mouse, Rat. This Survivin antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Survivin around the non-phosphorylation site of T34 |
![]() Survivin Polyclonal Antibody |
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ABP54791-01ml | Abbkine | 0.1ml | EUR 289 |
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Description: A polyclonal antibody for detection of Survivin from Human, Mouse, Rat. This Survivin antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Survivin around the non-phosphorylation site of T34 |
![]() Survivin Polyclonal Antibody |
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ABP54791-02ml | Abbkine | 0.2ml | EUR 414 |
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Description: A polyclonal antibody for detection of Survivin from Human, Mouse, Rat. This Survivin antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Survivin around the non-phosphorylation site of T34 |
![]() Survivin Polyclonal Antibody |
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ABP54792-003ml | Abbkine | 0.03ml | EUR 158 |
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Description: A polyclonal antibody for detection of Survivin from Human, Mouse, Rat. This Survivin antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Survivin around the non-phosphorylation site of T117 |
![]() Survivin Polyclonal Antibody |
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ABP54792-01ml | Abbkine | 0.1ml | EUR 289 |
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Description: A polyclonal antibody for detection of Survivin from Human, Mouse, Rat. This Survivin antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Survivin around the non-phosphorylation site of T117 |
![]() Survivin Polyclonal Antibody |
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ABP54792-02ml | Abbkine | 0.2ml | EUR 414 |
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Description: A polyclonal antibody for detection of Survivin from Human, Mouse, Rat. This Survivin antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Survivin around the non-phosphorylation site of T117 |
![]() Survivin Monoclonal Antibody |
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ABM40193-003ml | Abbkine | 0.03ml | EUR 158 |
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Description: A monoclonal antibody for detection of Survivin from Human, Rat. This Survivin antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein |
![]() Survivin Monoclonal Antibody |
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ABM40193-01ml | Abbkine | 0.1ml | EUR 289 |
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Description: A monoclonal antibody for detection of Survivin from Human, Rat. This Survivin antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein |
![]() Survivin Monoclonal Antibody |
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ABM40193-02ml | Abbkine | 0.2ml | EUR 414 |
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Description: A monoclonal antibody for detection of Survivin from Human, Rat. This Survivin antibody is for WB, IHC-P. It is affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in mouse by using as an immunogen recombinant protein |
![]() Survivin (BIRC5) Antibody |
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20-abx326671 | Abbexa |
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![]() Survivin (BIRC5) Antibody |
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20-abx326820 | Abbexa |
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![]() Survivin (BIRC5) Antibody |
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20-abx214437 | Abbexa |
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![]() Survivin (BIRC5) Antibody |
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20-abx214741 | Abbexa |
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![]() Survivin (BIRC5) Antibody |
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20-abx329628 | Abbexa |
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![]() Survivin (BIRC5) Antibody |
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abx412141-01mg | Abbexa | 0.1 mg | EUR 704 |
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![]() Survivin (BIRC5) Antibody |
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abx412488-01mg | Abbexa | 0.1 mg | EUR 509 |
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![]() Survivin (BIRC5) Antibody |
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abx430862-200ul | Abbexa | 200 ul | EUR 384 |
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![]() SURVIVIN (BIRC5) Antibody |
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abx238402-100ug | Abbexa | 100 ug | EUR 481 |
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![]() SURVIVIN-Specific Antibody |
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abx238403-100ug | Abbexa | 100 ug | EUR 481 |
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![]() Survivin (Surv) Antibody |
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20-abx178509 | Abbexa |
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![]() Survivin antibody (Thr117) |
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70R-36507 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit polyclonal Survivin antibody (Thr117) |
![]() Survivin antibody (Thr34) |
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70R-36960 | Fitzgerald | 100 ug | EUR 327 |
Description: Rabbit Polyclonal Survivin antibody (Thr34) |
Anti-Junctional Adhesion Molecule 1 Rabbit Monoclonal Antibody
- Based on morphologic proof from these analysis of BBB injury, the authors elaborated a singular EC system of modified caveolae that purportedly fused collectively forming transendothelial cell channels, and later comparable EC profiles outlined as vesiculo-canalicular or vesiculo-tubular buildings (VTS, Lossinsky, et al., 1999).
Human Anti-SSA/Ro Antibody (anti-Ro) ELISA Kit
- These EC buildings had been seen in affiliation with elevated BBB permeability of tracers along with exogenously injected HRP, normally excluded from the intercellular milieu of the CNS. Subsequent analysis of non-BBB-type tumor ECs determined that the EC VTS and totally different vesicular buildings had been outlined by others as vesiculo-vacuolar organelles (VVOs, Kohn et al., 1992; Dvorak et al., 1996). Collectively, these buildings appear to indicate a form of anatomical gateway to the CNS potential serving as conduits.
B-Lymphocyte Cell Adhesion Molecule (BL-CAM) Antibody
- Nonetheless, these CNS conduits develop to be patent solely in damaged ECs for the passage of macromolecules, and purportedly for inflammatory and neoplastic cells as successfully (Lossinsky et al., 1999). On this evaluation, we focus consideration on the similarities and variations between caveolae, fused racemic vesicular bundles, endothelial tubules and channels (VTS and the VVOs) which may be manifest in common, non-BBB-type blood vessels, and throughout the BBB after injury.
- This evaluation will present proof that the sooner analysis by the authors and totally different researchers established a framework for subsequent transmission (TEM), scanning (SEM) and high-voltage electron microscopic (HVEM) investigations concerning ultrastructural, ultracytochemical and immunoultra-structural alterations of the cerebral ECs and the mechanisms of the BBB transport that occurs after CNS injury.
- This evaluation won’t be supposed to include all the numerous observations that’s maybe included in a fundamental historic overview of the occasion of the EC channel hypothesis, nonetheless it’s going to speak about various of the foremost contributions. We now have tried to present a number of of the structural proof that helps our early contributions and other people made by totally different investigators by highlighting important choices of these EC buildings which may be manifest throughout the injured BBB. We now have centered on presently established concepts and guidelines related to mechanisms for the transendothelial transport of macromolecules after CNS injury and likewise present a vital appraisal of some of this literature.
Recombinant Human Intercellular Adhesion Molecule-1
- Lastly, we describe newer concepts of transBBB avenues for viruses, along with HIV-1, bacterial and mycotic organisms, along with inflammatory and neoplastic cell adhesion and migration all through the injured mammalian BBB. Data from analysis of EC-related adhesion molecules, every from the literature and from the creator’s experimental outcomes and observations made in several laboratories, along with from non-public communications underscore the importance of the adhesion molecules in
![]() Tivantinib |
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B1546-5 | Biovision | EUR 142 |
![]() Tivantinib |
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HY-50686 | MedChemExpress | 5mg | EUR 133 |
![]() Tivantinib (ARQ 197) |
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A8325-100 | ApexBio | 100 mg | EUR 490 |
Description: Tivantinib (ARQ 197) is an oral, non?adenosine triphosphate-competitive, selective, small-molecule met proto-oncogene (c-MET) inhibitor. The calculated inhibitory constant (Ki) for tivantinib to inhibit recombinant human c-MET was approximately 355 nmol/L. |
![]() Tivantinib (ARQ 197) |
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A8325-20 | ApexBio | 20 mg | EUR 189 |
Description: Tivantinib (ARQ 197) is an oral, non?adenosine triphosphate-competitive, selective, small-molecule met proto-oncogene (c-MET) inhibitor. The calculated inhibitory constant (Ki) for tivantinib to inhibit recombinant human c-MET was approximately 355 nmol/L. |
![]() Tivantinib (ARQ 197) |
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A8325-5 | ApexBio | 5 mg | EUR 113 |
Description: Tivantinib (ARQ 197) is an oral, non?adenosine triphosphate-competitive, selective, small-molecule met proto-oncogene (c-MET) inhibitor. The calculated inhibitory constant (Ki) for tivantinib to inhibit recombinant human c-MET was approximately 355 nmol/L. |
![]() Tivantinib (ARQ 197) |
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A8325-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 125 |
Description: Tivantinib (ARQ 197) is an oral, non?adenosine triphosphate-competitive, selective, small-molecule met proto-oncogene (c-MET) inhibitor. The calculated inhibitory constant (Ki) for tivantinib to inhibit recombinant human c-MET was approximately 355 nmol/L. |
![]() Tivantinib (ARQ 197) |
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A8325-S | ApexBio | Evaluation Sample | EUR 81 |
Description: Tivantinib (ARQ 197) is an oral, non?adenosine triphosphate-competitive, selective, small-molecule met proto-oncogene (c-MET) inhibitor. The calculated inhibitory constant (Ki) for tivantinib to inhibit recombinant human c-MET was approximately 355 nmol/L. |