The unlabeled antibody enzyme strategy of immunohistochemistry: preparation and properties of soluble antigen-antibody sophisticated (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes.
- Interleukin-10 (IL-10) impacts the growth and differentiation of many hemopoietic cells in vitro; notably, it is a potent suppressor of macrophage and T cell capabilities. In IL-10-deficient mice, generated by gene specializing in, lymphocyte enchancment and antibody responses are common, nonetheless most animals are growth retarded and anemic and endure from energy enterocolitis.
Anti-Mouse IgG, Rabbit Monoclonal Antibody
- Alterations in intestine embody intensive mucosal hyperplasia, inflammatory reactions, and aberrant expression of important histocompatibility sophisticated class II molecules on epithelia. In distinction, mutants saved beneath explicit pathogen-free circumstances develop solely an space irritation restricted to the proximal colon.
Human Serglycin Antibody (Biotin Conjugate)
- These outcomes level out that the bowel irritation inside the mutants originates from uncontrolled immune responses stimulated by enteric antigens and that IL-10 is a vital Antibodyintestinal tract.
Derazantinib Racemate |
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T10997-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Derazantinib Racemate |
Derazantinib Racemate |
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T10997-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Derazantinib Racemate |
Derazantinib Racemate |
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T10997-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Derazantinib Racemate |
Derazantinib Racemate |
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T10997-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Derazantinib Racemate |
Derazantinib Racemate |
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T10997-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Derazantinib Racemate |
DERA |
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enz-127 | ProSpec Tany | 5µg | EUR 60 |
Description: Recombinant E.Coli Deoxyribose-Phosphate Aldolase |
DERA |
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enz-170 | ProSpec Tany | 2µg | EUR 60 |
Description: Recombinant Human Deoxyribose-Phosphate Aldolase |
Lenti ORF particles, DERA (Myc-DDK tagged) - Human deoxyribose-phosphate aldolase (putative) (DERA), 200ul, >10^7 TU/mL |
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RC224461L1V | Origene Technologies GmbH | 200 µl | Ask for price |
Lenti ORF particles, DERA (mGFP-tagged) - Human deoxyribose-phosphate aldolase (putative) (DERA), 200ul, >10^7 TU/mL |
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RC224461L2V | Origene Technologies GmbH | 200 µl | Ask for price |
Lenti ORF particles, DERA (Myc-DDK tagged) - Human deoxyribose-phosphate aldolase (putative) (DERA), 200ul, >10^7 TU/mL |
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RC224461L3V | Origene Technologies GmbH | 200 µl | Ask for price |
Lenti ORF particles, DERA (mGFP-tagged) - Human deoxyribose-phosphate aldolase (putative) (DERA), 200ul, >10^7 TU/mL |
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RC224461L4V | Origene Technologies GmbH | 200 µl | Ask for price |
Lenti ORF particles, Dera (GFP-tagged) - Mouse 2-deoxyribose-5-phosphate aldolase homolog (C. elegans) (Dera), 200ul, >10^7 TU/mL |
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MR204598L4V | Origene Technologies GmbH | 200 µl | Ask for price |
DERA siRNA |
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20-abx914018 | Abbexa |
|
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DERA siRNA |
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20-abx914019 | Abbexa |
|
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Lenti ORF particles, Dera (Myc-DDK-tagged) - Mouse 2-deoxyribose-5-phosphate aldolase homolog (C. elegans) (Dera), 200ul, >10^7 TU/mL |
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MR204598L3V | Origene Technologies GmbH | 200 µl | Ask for price |
Deracoxib |
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540103 | MedKoo Biosciences | 50.0mg | EUR 250 |
Deracoxib |
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D281920 | Toronto Research Chemicals | 100mg | EUR 91 |
Description: 169590-41-4 |
Deracoxib |
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B1985-10 | Biovision | each | EUR 170.4 |
Deracoxib |
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B1091-100 | ApexBio | 100 mg | EUR 300 |
Description: Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). |
Deracoxib |
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B1091-1000 | ApexBio | 1g | EUR 768 |
Description: Selective COX-2 inhibitor |
Deracoxib |
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B1091-5.1 | ApexBio | 10 mM (in 1mL DMSO) | EUR 344.4 |
Description: Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). |
Deracoxib |
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B1091-500 | ApexBio | 500 mg | EUR 1062 |
Description: Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). |
Deracoxib |
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HY-17509 | MedChemExpress | 500mg | EUR 886.8 |
Deracoxib |
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T0484-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Deracoxib |
Deracoxib |
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T0484-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Deracoxib |
Deracoxib |
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T0484-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Deracoxib |
Deracoxib |
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T0484-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Deracoxib |
Deracoxib |
|||
T0484-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Deracoxib |
DERA Antibody |
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DF14813 | Affbiotech | 100ul | EUR 420 |
DERA Antibody |
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DF14813-100ul | Affinity Biosciences | 100ul | EUR 280 |
DERA Antibody |
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DF14813-200ul | Affinity Biosciences | 200ul | EUR 350 |
DERA (untagged)-Human deoxyribose-phosphate aldolase (putative) (DERA) |
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SC304371 | Origene Technologies GmbH | 10 µg | Ask for price |
Deracoxib-d4 |
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D281922 | Toronto Research Chemicals | 25mg | EUR 4500 |
Description: 1794780-24-7 |
DERA ELISA KIT|Human |
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EF004853 | Lifescience Market | 96 Tests | EUR 826.8 |
DERA protein (His tag) |
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80R-1954 | Fitzgerald | 50 ug | EUR 329 |
Description: Recombinant human DERA protein |
DERA (GFP-tagged) - Human deoxyribose-phosphate aldolase (putative) (DERA) |
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RG224461 | Origene Technologies GmbH | 10 µg | Ask for price |
Deramciclane |
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HY-101630 | MedChemExpress | 10mg | EUR 1183.2 |
Deramciclane |
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T10996-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Deramciclane |
Deramciclane |
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T10996-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Deramciclane |
Deramciclane |
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T10996-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Deramciclane |
Deramciclane |
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T10996-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Deramciclane |
Deramciclane |
|||
T10996-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Deramciclane |
DERA (Myc-DDK-tagged)-Human deoxyribose-phosphate aldolase (putative) (DERA) |
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RC224461 | Origene Technologies GmbH | 10 µg | Ask for price |
DERA ORF Vector (Human) (pORF) |
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ORF018210 | ABM | 1.0 ug DNA | EUR 486 |
Dera ORF Vector (Mouse) (pORF) |
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ORF042935 | ABM | 1.0 ug DNA | EUR 607.2 |
DERA 3'UTR GFP Stable Cell Line |
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TU055831 | ABM | 1.0 ml | EUR 1672.8 |
Dera 3'UTR GFP Stable Cell Line |
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TU155079 | ABM | 1.0 ml | Ask for price |
Dera (untagged) - Mouse 2-deoxyribose-5-phosphate aldolase homolog (C. elegans) (Dera), (10ug) |
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MC203919 | Origene Technologies GmbH | 10 µg | Ask for price |
Mouse DERA shRNA Plasmid |
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20-abx981975 | Abbexa |
|
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Human DERA shRNA Plasmid |
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20-abx959494 | Abbexa |
|
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Dera (Myc-DDK-tagged) - Mouse 2-deoxyribose-5-phosphate aldolase homolog (C. elegans) (Dera) |
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MR204598 | Origene Technologies GmbH | 10 µg | Ask for price |
OOPA00129-5UG - DERA E.coli |
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OOPA00129-5UG | Aviva Systems Biology | 5ug | EUR 69 |
Human DERA knockout cell line |
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ABC-KH4127 | AcceGen | 1 vial | Ask for price |
Description: Human DERA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
Lenti ORF clone of Dera (mGFP-tagged) - Mouse 2-deoxyribose-5-phosphate aldolase homolog (C. elegans) (Dera) |
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MR204598L4 | Origene Technologies GmbH | 10 µg | Ask for price |
DERA (untagged) - Human deoxyribose-phosphate aldolase (putative) (DERA), transcript variant 2 |
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SC334990 | Origene Technologies GmbH | 10 µg | Ask for price |
Human DERA knockdown cell line |
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ABC-KD4127 | AcceGen | 1 vial | Ask for price |
Description: Human DERA knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
Human DERA Protein Lysate 20ug |
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IHUDERAPLLY20UG | Innovative research | each | EUR 213 |
Description: Human DERA Protein Lysate 20ug |
Deramciclane fumarate |
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T27149-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Deramciclane fumarate |
Deramciclane fumarate |
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T27149-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Deramciclane fumarate |
Deramciclane fumarate |
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T27149-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Deramciclane fumarate |
Deramciclane fumarate |
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T27149-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Deramciclane fumarate |
Deramciclane fumarate |
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T27149-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Deramciclane fumarate |
Lenti ORF clone of Dera (Myc-DDK-tagged) - Mouse 2-deoxyribose-5-phosphate aldolase homolog (C. elegans) (Dera) |
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MR204598L3 | Origene Technologies GmbH | 10 µg | Ask for price |
DERA (myc-DDK-tagged) - Human deoxyribose-phosphate aldolase (putative) (DERA), transcript variant 2 |
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RC237096 | Origene Technologies GmbH | 10 µg | Ask for price |
DERA Protein Vector (Human) (pPM-C-HA) |
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PV072839 | ABM | 500 ng | EUR 662.4 |
DERA Protein Vector (Mouse) (pPM-C-HA) |
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PV171740 | ABM | 500 ng | EUR 723.6 |
OOPA00137-5UG - DERA E.coli Protein |
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OOPA00137-5UG | Aviva Systems Biology | 5ug | EUR 70 |
DERA Protein Vector (Human) (pPB-C-His) |
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PV072837 | ABM | 500 ng | EUR 662.4 |
DERA Protein Vector (Human) (pPB-N-His) |
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PV072838 | ABM | 500 ng | EUR 662.4 |
DERA Protein Vector (Human) (pPM-C-His) |
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PV072840 | ABM | 500 ng | EUR 662.4 |
DERA Protein Vector (Mouse) (pPB-C-His) |
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PV171738 | ABM | 500 ng | EUR 723.6 |
DERA Protein Vector (Mouse) (pPB-N-His) |
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PV171739 | ABM | 500 ng | EUR 723.6 |
DERA Protein Vector (Mouse) (pPM-C-His) |
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PV171741 | ABM | 500 ng | EUR 723.6 |
DERA Recombinant Protein (Human) |
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RP054627 | ABM | 100 ug | Ask for price |
DERA Recombinant Protein (Mouse) |
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RP128801 | ABM | 100 ug | Ask for price |
DERA 3'UTR Luciferase Stable Cell Line |
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TU005831 | ABM | 1.0 ml | EUR 1672.8 |
Dera 3'UTR Luciferase Stable Cell Line |
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TU105079 | ABM | 1.0 ml | Ask for price |
OCOA10480-20UG - DERA Protein Lysate |
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OCOA10480-20UG | Aviva Systems Biology | 20ug | EUR 169 |
DERA sgRNA CRISPR Lentivector set (Human) |
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K0585101 | ABM | 3 x 1.0 ug | EUR 406.8 |
Dera sgRNA CRISPR Lentivector set (Mouse) |
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K3359001 | ABM | 3 x 1.0 ug | EUR 406.8 |
Building of an HIV gp120 envelope glycoprotein in sophisticated with the CD4 receptor and a neutralizing human antibody.
BACKGROUND
Victims with superior squamous-cell non-small-cell lung most cancers (NSCLC) who’ve sickness growth all through or after first-line chemotherapy have restricted treatment decisions. This randomized, open-label, worldwide, part Three analysis evaluated the efficacy and safety of nivolumab, a totally human IgG4 programmed dying 1 (PD-1) immune-checkpoint-inhibitor antibody, as in distinction with docetaxel on this affected particular person inhabitants.
Mouse Monoclonal Anti-Human CD4 IgG
METHODS
We randomly assigned 272 victims to acquire nivolumab, at a dose of three mg per kilogram of physique weight every 2 weeks, or docetaxel, at a dose of 75 mg per sq. meter of body-surface area every Three weeks. The primary end degree was basic
survival.
SAR405 R enantiomer |
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T12831-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: SAR405 R enantiomer |
RSV604 (R enantiomer) |
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T12775-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: RSV604 (R enantiomer) |
RSV604 (R enantiomer) |
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T12775-1g | TargetMol Chemicals | 1g | Ask for price |
Description: RSV604 (R enantiomer) |
RSV604 (R enantiomer) |
|||
T12775-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: RSV604 (R enantiomer) |
RSV604 (R enantiomer) |
|||
T12775-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: RSV604 (R enantiomer) |
RSV604 (R enantiomer) |
|||
T12775-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: RSV604 (R enantiomer) |
THK5351 (R enantiomer) |
|||
HY-101183A | MedChemExpress | 10mg | EUR 1630.8 |
THK5351 (R enantiomer) |
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T39541-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: THK5351 (R enantiomer) |
THK5351 (R enantiomer) |
|||
T39541-1g | TargetMol Chemicals | 1g | Ask for price |
Description: THK5351 (R enantiomer) |
THK5351 (R enantiomer) |
|||
T39541-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: THK5351 (R enantiomer) |
THK5351 (R enantiomer) |
|||
T39541-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: THK5351 (R enantiomer) |
THK5351 (R enantiomer) |
|||
T39541-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: THK5351 (R enantiomer) |
THK5351 R enantiomer |
|||
T13151-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: THK5351 R enantiomer |
THK5351 R enantiomer |
|||
T13151-1g | TargetMol Chemicals | 1g | Ask for price |
Description: THK5351 R enantiomer |
THK5351 R enantiomer |
|||
T13151-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: THK5351 R enantiomer |
THK5351 R enantiomer |
|||
T13151-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: THK5351 R enantiomer |
THK5351 R enantiomer |
|||
T13151-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: THK5351 R enantiomer |
GLPG0492 (R enantiomer) |
|||
HY-18102A | MedChemExpress | 10mM/1mL | EUR 696 |
GLPG0492 (R enantiomer) |
|||
T11410-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: GLPG0492 (R enantiomer) |
GLPG0492 (R enantiomer) |
|||
T11410-1g | TargetMol Chemicals | 1g | Ask for price |
Description: GLPG0492 (R enantiomer) |
GLPG0492 (R enantiomer) |
|||
T11410-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: GLPG0492 (R enantiomer) |
GLPG0492 (R enantiomer) |
|||
T11410-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: GLPG0492 (R enantiomer) |
GLPG0492 (R enantiomer) |
|||
T11410-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: GLPG0492 (R enantiomer) |
Duvelisib (R enantiomer) |
|||
HY-17044A | MedChemExpress | 10mg | EUR 253.2 |
Duvelisib (R enantiomer) |
|||
T11129-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Duvelisib (R enantiomer) |
Duvelisib (R enantiomer) |
|||
T11129-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Duvelisib (R enantiomer) |
Duvelisib (R enantiomer) |
|||
T11129-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Duvelisib (R enantiomer) |
Duvelisib (R enantiomer) |
|||
T11129-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Duvelisib (R enantiomer) |
Duvelisib (R enantiomer) |
|||
T11129-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Duvelisib (R enantiomer) |
Talarozole (R enantiomer) |
|||
HY-14802 | MedChemExpress | 50mg | EUR 4027.2 |
Siremadlin R Enantiomer |
|||
HY-18658A | MedChemExpress | 10mM/1mL | EUR 800.4 |
Bitopertin (R enantiomer) |
|||
HY-10809A | MedChemExpress | 1mg | EUR 639.6 |
Bitopertin (R enantiomer) |
|||
T10552-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Bitopertin (R enantiomer) |
Bitopertin (R enantiomer) |
|||
T10552-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Bitopertin (R enantiomer) |
Bitopertin (R enantiomer) |
|||
T10552-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Bitopertin (R enantiomer) |
Bitopertin (R enantiomer) |
|||
T10552-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Bitopertin (R enantiomer) |
Bitopertin (R enantiomer) |
|||
T10552-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Bitopertin (R enantiomer) |
Siremadlin (R Enantiomer) |
|||
T12274-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Siremadlin (R Enantiomer) |
Siremadlin (R Enantiomer) |
|||
T12274-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Siremadlin (R Enantiomer) |
Siremadlin (R Enantiomer) |
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T12274-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Siremadlin (R Enantiomer) |
Siremadlin (R Enantiomer) |
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T12274-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Siremadlin (R Enantiomer) |
Siremadlin (R Enantiomer) |
|||
T12274-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Siremadlin (R Enantiomer) |
Talarozole (R enantiomer) |
|||
T13422L-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Talarozole (R enantiomer) |
Talarozole (R enantiomer) |
|||
T13422L-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Talarozole (R enantiomer) |
Talarozole (R enantiomer) |
|||
T13422L-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Talarozole (R enantiomer) |
Talarozole (R enantiomer) |
|||
T13422L-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Talarozole (R enantiomer) |
Talarozole (R enantiomer) |
|||
T13422L-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Talarozole (R enantiomer) |
Carfilzomib (R)-Enantiomer |
|||
C183555 | Toronto Research Chemicals | 100mg | EUR 11200 |
Fulvestrant R enantiomer |
|||
HY-13636B | MedChemExpress | 10mg | EUR 2539.2 |
Seviteronel (R enantiomer) |
|||
HY-15996A | MedChemExpress | 50mg | EUR 2539.2 |
Refametinib (R enantiomer) |
|||
HY-10216 | MedChemExpress | 1mg | EUR 639.6 |
Refametinib (R enantiomer) |
|||
T12697-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Refametinib (R enantiomer) |
Refametinib (R enantiomer) |
|||
T12697-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Refametinib (R enantiomer) |
Refametinib (R enantiomer) |
|||
T12697-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Refametinib (R enantiomer) |
Refametinib (R enantiomer) |
|||
T12697-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Refametinib (R enantiomer) |
Refametinib (R enantiomer) |
|||
T12697-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Refametinib (R enantiomer) |
Fulvestrant (R enantiomer) |
|||
T11334-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Fulvestrant (R enantiomer) |
Fulvestrant (R enantiomer) |
|||
T11334-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Fulvestrant (R enantiomer) |
Fulvestrant (R enantiomer) |
|||
T11334-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Fulvestrant (R enantiomer) |
Fulvestrant (R enantiomer) |
|||
T11334-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Fulvestrant (R enantiomer) |
Fulvestrant (R enantiomer) |
|||
T11334-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Fulvestrant (R enantiomer) |
Seviteronel R enantiomer |
|||
T13312-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Seviteronel R enantiomer |
Seviteronel R enantiomer |
|||
T13312-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Seviteronel R enantiomer |
Seviteronel R enantiomer |
|||
T13312-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Seviteronel R enantiomer |
Seviteronel R enantiomer |
|||
T13312-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Seviteronel R enantiomer |
Seviteronel R enantiomer |
|||
T13312-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Seviteronel R enantiomer |
Morinidazole (R enantiomer) |
|||
HY-15781A | MedChemExpress | 10mg | EUR 886.8 |
Morinidazole (R enantiomer) |
|||
T12096-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Morinidazole (R enantiomer) |
Morinidazole (R enantiomer) |
|||
T12096-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Morinidazole (R enantiomer) |
Morinidazole (R enantiomer) |
|||
T12096-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Morinidazole (R enantiomer) |
Morinidazole (R enantiomer) |
|||
T12096-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Morinidazole (R enantiomer) |
Morinidazole (R enantiomer) |
|||
T12096-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Morinidazole (R enantiomer) |
Leu-AMS R enantiomer |
|||
HY-108900A | MedChemExpress | 1mg | EUR 680.4 |
Leu-AMS R enantiomer |
|||
T11841-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Leu-AMS R enantiomer |
Leu-AMS R enantiomer |
|||
T11841-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Leu-AMS R enantiomer |
Leu-AMS R enantiomer |
|||
T11841-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Leu-AMS R enantiomer |
Leu-AMS R enantiomer |
|||
T11841-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Leu-AMS R enantiomer |
Leu-AMS R enantiomer |
|||
T11841-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Leu-AMS R enantiomer |
ARRY-520 R enantiomer |
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A3188-10 | ApexBio | 10 mg | EUR 270 |
Description: KSP inhibitor |
ARRY-520 R enantiomer |
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A3188-100 | ApexBio | 100 mg | EUR 1965 |
Description: KSP inhibitor |
ARRY-520 R enantiomer |
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A3188-5 | ApexBio | 5 mg | EUR 151 |
Description: KSP inhibitor |
ARRY-520 R enantiomer |
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A3188-50 | ApexBio | 50 mg | EUR 1164 |
Description: KSP inhibitor |
Ribocil-C R enantiomer |
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HY-19488B | MedChemExpress | 5mg | EUR 968.4 |
Ribocil-C (R enantiomer) |
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T39663-10mg | TargetMol Chemicals | 10mg | Ask for price |
Description: Ribocil-C (R enantiomer) |
Ribocil-C (R enantiomer) |
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T39663-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Ribocil-C (R enantiomer) |
Ribocil-C (R enantiomer) |
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T39663-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Ribocil-C (R enantiomer) |
Ribocil-C (R enantiomer) |
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T39663-50mg | TargetMol Chemicals | 50mg | Ask for price |
Description: Ribocil-C (R enantiomer) |
Ribocil-C (R enantiomer) |
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T39663-5mg | TargetMol Chemicals | 5mg | Ask for price |
Description: Ribocil-C (R enantiomer) |
Ribocil-C R enantiomer |
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T12723-1g | TargetMol Chemicals | 1g | Ask for price |
Description: Ribocil-C R enantiomer |
Ribocil-C R enantiomer |
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T12723-1mg | TargetMol Chemicals | 1mg | Ask for price |
Description: Ribocil-C R enantiomer |
RESULTS
The median basic survival was 9.2 months (95% confidence interval [CI], 7.Three to 13.3) with nivolumab versus 6.Zero months (95% CI, 5.1 to 7.3) with docetaxel. The prospect of dying was 41% lower with nivolumab than with docetaxel (hazard ratio, 0.59; 95% CI, 0.44 to 0.79; P<0.001). At 1 12 months, the final survival cost was 42% (95% CI, 34 to 50) with nivolumab versus 24% (95% CI, 17 to 31) with docetaxel. The response cost was 20% with nivolumab versus 9% with docetaxel (P=0.008).
The median progression-free survival was 3.5 months with nivolumab versus 2.eight months with docetaxel (hazard ratio for dying or sickness growth, 0.62; 95% CI, 0.47 to 0.81; P<0.001). The expression of the PD-1 ligand (PD-L1) was neither prognostic nor predictive of revenue. Treatment-related hostile events of grade Three or 4 had been reported in 7% of the victims inside the nivolumab group as in distinction with 55% of those inside the docetaxel group.
CONCLUSIONS
Amongst victims with superior, beforehand dealt with squamous-cell NSCLC, basic survival, response cost, and progression-free survival had been significantly increased with nivolumab than with docetaxel, regardless of PD-L1 expression stage. (Funded by Bristol-Myers Squibb; CheckMate 017 ClinicalTrials.gov amount, NCT01642004.).
- The entry of human immunodeficiency virus (HIV) into cells requires the sequential interaction of the viral exterior envelope glycoprotein, gp120, with the CD4 glycoprotein and a chemokine receptor on the cell ground. These interactions provoke a fusion of the viral and cellular membranes.
- Although gp120 can elicit virus-neutralizing antibodies, HIV eludes the immune system. We’ve now solved the X-ray crystal building at 2.5 A call of an HIV-1 gp120 core complexed with a two-domain fragment of human CD4 and an antigen-binding fragment of a neutralizing antibody that blocks chemokine-receptor binding.
Rabbit Anti-Mouse IgG2a (heavy-chain sp.), unlabeled
- The development reveals a cavity-laden CD4-gp120 interface, a conserved binding web site for the chemokine receptor, proof for a conformational change upon CD4 binding, the character of a CD4-induced antibody epitope, and explicit mechanisms for immune evasion. Our outcomes current a framework for understanding the sophisticated biology of HIV entry into cells and will info efforts to intervene.