PD-L2 Rabbit Polyclonal Antibody

PD-L2 Rabbit Polyclonal Antibody

To Order: garrett@bioworldantibodies.com

PD-L2 Peptide
4063P 0.05 mg
EUR 197.7
Description: (IN) PD-L2 peptide

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody
A64216-020 20 ul
EUR 117.7

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody
A64216-050 50 ul
EUR 302.5

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody
A64216-100 100 ul
EUR 423.5

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody
A64216
  • EUR 684.66
  • EUR 117.70
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

PD-L2 Recombinant Protein
91-721 0.05 mg
EUR 821.4
Description: Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart, placenta, pancreas, lung and liver; it is weakly expressed in the spleen, lymph nodes, and thymus. PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

PD-L2 Recombinant Protein
92-497 0.05 mg
EUR 437.1
Description: Programmed cell death 1 ligand 2 (PD-L2), also known as butyrophilin B7-DC or PDCD1 ligand 2, belongs to the member of B7 family which can regulate the activation and tolerance of T cells. PD-L2 is one ligand for Programmed cell death 1(PD-1), and the other is PD-L1. These two ligands shares 34% aa sequence identity. Mouse PD-L2 gene encodes a 273 amino acids (aa) protein with a putative 19 aa signal peptide, a 201 aa extracellular region , a 21 aa transmembrane domain and a 32 aa cytoplasmic region. The mouse PD-L2 gene is highly expressed in heart, placenta, pancreas, lung and liver while expressed weakly in spleen, lymph nodes and thymus. Besides, the expression of PD-L2 gene can be induced on dendritic cells grown from peripheral blood mononuclear cells under CSF2 and IL4/interleukin-4 treatment, and up-regulated by IFNG/IFN-gamma stimulation in monocytes. PD-L2 usually functions in a PDCD1-independent manner and is involved in regulating costimulatory signal which is essential for T-cell proliferation and IFNG production. Recent studies demonstrate that the expression of PD-L2 on the tumor cells promotes CD8 T cell–mediated rejection of tumor cells, at both the induction and effector phase of antitumor immunity. Moreover, PD-L2 binds to PD-1 cells and enhances T cell killing in a PD-1–independent mechanism.

PD-L2 Recombinant Protein
96-938 0.1 mg
EUR 651.3
Description: Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

PD-L2 Recombinant Protein
97-021 0.1 mg
EUR 651.3
Description: Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

PD-L2 Recombinant Protein
97-022 0.1 mg
EUR 651.3
Description: Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Ribosome-inactivating protein PD-L1/PD-L2 Antibody
1-CSB-PA306294LA01PJJ
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Ribosome-inactivating protein PD-L1/PD-L2. Recognizes Ribosome-inactivating protein PD-L1/PD-L2 from Phytolacca dioica. This antibody is Unconjugated. Tested in the following application: ELISA

Ribosome-inactivating protein PD-L1 / PD-L2 Antibody
20-abx319445
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

PD-1:PD-L2 Homogeneous Assay Kit
72015 384 rxns.
EUR 1070
Description: The PD-1:PD-L2 Homogeneous Assay Kit is designed to measure the_x000D_inhibition of PD-1 binding to PD-L2. With this kit, only three simple steps on a microtiter_x000D_plate are required. First, a sample containing PD-1 and an inhibitor of choice is incubated with_x000D_the biotinylated PD-L2 for 60 minutes. Next, acceptor beads are added, then donor beads,_x000D_followed by reading the Alpha-counts.

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody, HRP Conjugated
A64217-050 50 ul
EUR 302.5

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody, HRP Conjugated
A64217-100 100 ul
EUR 423.5

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody, FITC Conjugated
A64218-050 50 ul
EUR 302.5

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody, FITC Conjugated
A64218-100 100 ul
EUR 423.5

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody, Biotin Conjugated
A64219-050 50 ul
EUR 302.5

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody, Biotin Conjugated
A64219-100 100 ul
EUR 423.5

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody, HRP Conjugated
A64217
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody, FITC Conjugated
A64218
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Ribosome-Inactivating Protein PD-L1/PD-L2 Polyclonal Antibody, Biotin Conjugated
A64219
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Ribosome-inactivating protein PD-L1 / PD-L2 Antibody (HRP)
20-abx319446
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ribosome-inactivating protein PD-L1 / PD-L2 Antibody (FITC)
20-abx319447
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Ribosome-inactivating protein PD-L1 / PD-L2 Antibody (Biotin)
20-abx319448
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

CD273 [PD-L2] Recombinant Protein
90-425 100 ug
EUR 651.3
Description: T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 (PD-L2) is one of two ligands for programmed death-1 (PD-1; CD279), a member of the CD28 family of immunoreceptors. The other identified ligand is PD-L1. CD273 is broadly expressed and also up regulated in a variety of tumor cell lines. On previously activated T cells, CD273 interaction with PD-1 inhibits TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. CD273 has a costimulatory function on resting T cells activated with suboptimal TCR signals.

CD273 [PD-L2] Recombinant Protein
90-427 100 ug
EUR 651.3
Description: T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 (PD-L2) is one of two ligands for programmed death-1 (PD-1; CD279), a member of the CD28 family of immunoreceptors. The other identified ligand is PD-L1. CD273 is broadly expressed and also up regulated in a variety of tumor cell lines. On previously activated T cells, CD273 interaction with PD-1 inhibits TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. CD273 has a costimulatory function on resting T cells activated with suboptimal TCR signals.

CD273 [PD-L2] Recombinant Protein
90-428 100 ug
EUR 651.3
Description: T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 (PD-L2) is one of two ligands for programmed death-1 (PD-1; CD279), a member of the CD28 family of immunoreceptors. The other identified ligand is PD-L1. CD273 is broadly expressed and also up regulated in a variety of tumor cell lines. On previously activated T cells, CD273 interaction with PD-1 inhibits TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. CD273 has a costimulatory function on resting T cells activated with suboptimal TCR signals.

PD-1:PD-L2 TR-FRET Assay Kit
72012 384 rxns.
EUR 1070
Description: The PD-1:PD-L2 TR-FRET Assay Kit is designed to measure the inhibition of PD-1 binding to_x000D_PD-L2 in a homogeneous 384 reaction format. Cell signaling through the PD-1 receptor upon_x000D_binding the PD-L2 ligand attenuates immune responses and is exploited by both tumors and_x000D_viruses. This FRET-based assay requires no time-consuming washing steps, making it_x000D_especially suitable for high throughput screening applications. The assay procedure is_x000D_straightforward and simple; a sample containing europium-labeled (Eu) PD-1, dye-labeled_x000D_acceptor, biotin-labeled PD-L2, and an inhibitor is incubated for two hours. Then, the_x000D_fluorescence intensity is measured using a fluorescence reader.

Ribosome-inactivating protein PD-L1/PD-L2 Antibody, HRP conjugated
1-CSB-PA306294LB01PJJ
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Ribosome-inactivating protein PD-L1/PD-L2. Recognizes Ribosome-inactivating protein PD-L1/PD-L2 from Phytolacca dioica. This antibody is HRP conjugated. Tested in the following application: ELISA

Ribosome-inactivating protein PD-L1/PD-L2 Antibody, FITC conjugated
1-CSB-PA306294LC01PJJ
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Ribosome-inactivating protein PD-L1/PD-L2. Recognizes Ribosome-inactivating protein PD-L1/PD-L2 from Phytolacca dioica. This antibody is FITC conjugated. Tested in the following application: ELISA

Ribosome-inactivating protein PD-L1/PD-L2 Antibody, Biotin conjugated
1-CSB-PA306294LD01PJJ
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Ribosome-inactivating protein PD-L1/PD-L2. Recognizes Ribosome-inactivating protein PD-L1/PD-L2 from Phytolacca dioica. This antibody is Biotin conjugated. Tested in the following application: ELISA

Phytolacca dioica Ribosome-inactivating protein PD-L1/PD-L2
1-CSB-EP306294PJJ
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Phytolacca dioica Ribosome-inactivating protein PD-L1/PD-L2 expressed in E.coli

PD-1:PD-L2[Biotinylated] Inhibitor Screening Assay Kit
72004 96 rxns.
EUR 1095
Description: The PD-1:PD-L2[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. The key to this kit is the high sensitivity of detection of biotin-labeled PD-L2 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, PD-1 is coated on a 96-well plate. Next, PD-L2 is incubated with PD-1 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

PD-1[Biotinylated]:PD-L2 Inhibitor Screening Assay Kit
72006 96 rxns.
EUR 1235
Description: The PD-L2 Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. The key to this kit is the high sensitivity of detection of biotin-labeled PD-1 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, PD-L2 is coated on a 96-well plate. Next, PD-1 is incubated with PD-L2 on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

PD-1:PD-L1/PD-L2 Cell-Based Inhibitor Screening Assay Kit
60800 96 rxns.
EUR 1070
Description: The PD-1/PD-L1 Inhibitor Screening Cell-Based Assay is a bioluminescent cell-based assay that can be used to screen and profile inhibitors of PD-1:PD-L1 or PD-1:PD-L2 interaction. The assay consists of two main components:_x000D_ • PD-1 Effector cells (PD-1/NFAT reporter-Jurkat cells): Reporter Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements and also constitutively expressing human PD-1. These cryopreserved cells are provided in a thaw-and-use format that does not require cell propagation._x000D_ • _x000D_Expression vectors for TCR activator, human PD-L1, and human PD-L2: Transfection-ready vectors are used to transfect cells to create the target cells that overexpress PD-L1 or PD-L2 and an engineered cell surface T cell receptor (TCR) activator._x000D_

PD-L2 (CD273), Fc fusion (Human)
71107 100 µg
EUR 330
Description: Human secreted Programmed Death Ligand 2 (PD-L2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, fused at the C-terminus to the Fc portion of human IgG1 expressed in a HEK293 cell expression system. MW = 49 kDa.

PD-1:PD-L2[Biotinylated] Inhibitor Screening Colorimetric Assay Kit
72017 96 rxns.
EUR 1095
Description: Cell signaling through the PD-1 receptor upon binding the PD-L2 ligand_x000D_attenuates immune responses and is exploited by both tumors and viruses. The PD-1:PDL2[_x000D_Biotinylated] Inhibitor Screening Colorimetric Assay Kit is designed for screening inhibitors of_x000D_PD-L2 ligand binding to PD-1 receptor. The key to this kit is the high affinity of biotin-labeled PD-L2 for streptavidin-HRP._x000D_Only a few simple steps on a microtiter plate are required for the assay. First, PD-1 is coated on_x000D_a 96-well plate. Next, PD-L2 is incubated with PD-1 on the plate. Finally, the plate is treated with_x000D_streptavidin-HRP followed by addition of a colorimetric HRP substrate to produce color, which_x000D_can then be measured using a UV/Vis spectrophotometer microplate reader.

PD-1[Biotinylated]:PD-L2 Inhibitor Screening Colorimetric Assay Kit
72019 96 rxns.
EUR 1095
Description: Cell signaling through the PD-1 receptor upon binding the PD-L2 ligand_x000D_attenuates immune responses and is exploited by both tumors and viruses. The PD-_x000D_1[Biotinylated]:PD-L2 Inhibitor Screening Colorimetric Assay Kit is designed for screening_x000D_inhibitors of PD-1 receptor binding to PD-L2 ligand. The key to this kit is the high affinity of biotin-labeled PD-1 for_x000D_streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First,_x000D_PD-L2 is coated on a 96-well plate. Next, PD-1 is incubated with PD-L2 on the plate. Finally, the_x000D_plate is treated with streptavidin-HRP followed by addition of a colorimetric HRP substrate_x000D_substrate to produce color, which can then be measured using a UV/Vis spectrophotometer_x000D_microplate reader.

PD-1:PD-L2 Cell-Based Inhibitor Screening Assay Kit
79378 96 rxns.
EUR 615
Description: The PD-1/PD-L2 Inhibitor Screening Cell-Based Assay is a bioluminescent cell-based assay that can be used to screen and profile inhibitors of the PD-1:PD-L2 interaction. The assay consists of two main components:_x000D_• Growth-Arrested PD-1 Effector cells (PD-1/NFAT reporter-Jurkat cells): Reporter Jurkat T cells expressing firefly luciferase gene under the control of NFAT response elements and also constitutively expressing Human PD-1. These cryopreserved cells are provided in a thaw-anduse format that does not require cell propagation. These cells are modified not to be expanded and are intended to be used in a single experiment._x000D_• Expression vectors for TCR activator and Human PD-L2: Transfection-ready vectors are used to transfect cells to create the target cells that overexpress PD-L2 and an engineered cell surface T cell receptor (TCR) activator.

Mouse Anti-Human CD273 (PD-L2) mAbConjugated Antibody
CCM031 100ul
EUR 476.4

Anti-CD273/ PD-L2 Antibody [TY25], Unconjugated-100ug
QAB101-100ug 100ug
EUR 270

PD-L2 Antibody / Programmed death ligand 2 / CD273
R32447 100 ug
EUR 419

PD-L2 Antibody / Programmed death ligand 2 / CD273
V8176-100UG 100 ug
EUR 499
Description: Recognizes a protein of about 31kDa, which is identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.

PD-L2 Antibody / Programmed death ligand 2 / CD273
V8176-20UG 20 ug
EUR 219
Description: Recognizes a protein of about 31kDa, which is identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.

PD-L2 Antibody / Programmed death ligand 2 / CD273
V8176SAF-100UG 100 ug
EUR 499
Description: Recognizes a protein of about 31kDa, which is identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.

PD-L2 Antibody / Programmed death ligand 2 / CD273
V7546-100UG 100 ug
EUR 499
Description: PD-L2/PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. [UniProt]

PD-L2 Antibody / Programmed death ligand 2 / CD273
V7546-20UG 20 ug
EUR 219
Description: PD-L2/PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. [UniProt]

PD-L2 Antibody / Programmed death ligand 2 / CD273
V7546SAF-100UG 100 ug
EUR 499
Description: PD-L2/PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. [UniProt]

PD-L2 Antibody / Programmed death ligand 2 / CD273
V7581-100UG 100 ug
EUR 499
Description: Recognizes a protein identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.

PD-L2 Antibody / Programmed death ligand 2 / CD273
V7581-20UG 20 ug
EUR 219
Description: Recognizes a protein identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.

PD-L2 Antibody / Programmed death ligand 2 / CD273
V7581SAF-100UG 100 ug
EUR 499
Description: Recognizes a protein identified as PD-L2 (same as PDCD1LG2). Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator). The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease.

Mouse Anti-Human CD273 (PD-L2) mAb
CM031-100ug 100ug
EUR 250.8

Mouse Anti-Human CD273 (PD-L2) mAb
CM031-25ug 25ug
EUR 154.8

CD273 [PD-L2] non-lytic Recombinant Protein
90-426 100 ug
EUR 651.3
Description: T cells require a signal induced by the engagement of the T cell receptor and a €œcostimulatory€ signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273 is one of two ligands for programmed death-1 (PD-1; CD279), a member of the CD28 family of immunoreceptors. The other identified ligand is PD-L1. CD273 is broadly expressed and also up regulated in a variety of tumor cell lines. On previously activated T cells, CD273 interaction with PD-1 inhibits TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. CD273 has a costimulatory function on resting T cells activated with suboptimal TCR signals.

PD-L2, Fc Chimera (HEK293-expressed), Human
HY-P7399 50ug
EUR 321.6

TranslationBlocker Human PD-L2/ CD273 siRNA, 10nmol
QX8-10nmol 10nmol
EUR 452.4

TranslationBlocker Human PD-L2/ CD273 siRNA, 2nmol
QX8-2nmol 2nmol
EUR 331.2

Recombinant PD-L2 Protein (Met1-Pro219) [His]
VAng-Cr3818-100g 100 µg
EUR 973.2
Description: Recombinant PD-L2 Protein (Met1-Pro219) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 40-45 kDa. (Uniprot ID: Q9BQ51)

PD-L2 / TCR Activator Mammalian Expression Kit
60620 500 rxns.
EUR 565
Description: The recombinant expression vectors are designed to express human engineered T cell receptor (TCR) activator and human PD-L2 (GenBank Accession #NM_025239) in mammalian cells. The transfected cells can be used in conjunction with PD-1/NFAT Reporter/Jurkat T cells (BPS #60535) to study the interactions of PD-1 with PD-L2 ligand in a cellular context and screen for modulators of this signaling pathway._x000D_In this assay, PD-1/NFAT Reporter/Jurkat T cells are used as effector cells; HEK293 cells overexpressing PD-L1 (or PD-L2) and an engineered T cell receptor (TCR) activator are used as target cells. When these two cells are co-cultivated, TCR complexes on effector cells are activated by TCR activator on target cells, resulting in expression of the NFAT luciferase reporter. However, PD1 and PD-L1 or PD-L2 ligation prevents TCR activation and suppresses the NFAT-responsive luciferase activity. This inhibition can be specifically reversed by anti-PD1 or anti-PD-L1 antibodies. PD1, PD-L1, or PD-L2 neutralizing antibodies block PD1:PD-L1 and/or PD1:PD-L2 interaction and promote T cell activation, resulting in reactivation of the NFAT responsive luciferase reporter.

L2 Polyclonal Antibody
A56895-020 20 ul
EUR 117.7

L2 Polyclonal Antibody
A56895-050 50 ul
EUR 302.5

L2 Polyclonal Antibody
A56895-100 100 ul
EUR 423.5

L2 Polyclonal Antibody
A56907-020 20 ul
EUR 117.7

L2 Polyclonal Antibody
A56907-050 50 ul
EUR 302.5

L2 Polyclonal Antibody
A56907-100 100 ul
EUR 423.5

L2 Polyclonal Antibody
A56895
  • EUR 684.66
  • EUR 117.70
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

L2 Polyclonal Antibody
A56907
  • EUR 684.66
  • EUR 117.70
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

Human PD-L2/B7-DC PicoKine ELISA Kit
EK1447 96 wells
EUR 510
Description: For Quantitative Detection of human PD-L2 in cell culture supernates, serum and plasma (heparin, EDTA).

ELISA kit for Human PD-L2/B7-DC
EK5768 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human PD-L2/B7-DC in samples from serum, plasma, tissue homogenates and other biological fluids.

Recombinant Human B7-DC/PD-L2/CD273 Protein
RP00150 20 μg
EUR 231.6

Recombinant Mouse PD-L2/B7-DC/CD273 Protein
RP00660 10 μg
EUR 174

Recombinant Human B7-DC/PD-L2/CD273 Protein
RP00988 10 μg
EUR 186

Human CellExp? PD-L2 / B7-DC, mouse recombinant
P1087-10 each
EUR 170.4

Human CellExp? PD-L2 / B7-DC, mouse recombinant
P1087-50 each
EUR 548.4

PD-L2 (CD273), Fc fusion, Biotin-labeled (Human)
71108 50 µg
EUR 440
Description: Human secreted Programmed Death Ligand 2 (PD-L2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, fused at the C-terminus to the Fc portion of human IgG1, with C-terminal Avitag ™ expressed in a HEK293 cell expression system and enzymatically biotinlabeled using Avi-tag™ technology. MW = 51 kDa.

PD-L2 / TCR activator - CHO Recombinant Cell Line
79632 2 vials
EUR 9400
Description: Recombinant CHO-K1 cells constitutively expressing human PD-L2 (Programmed Cell Death 1 Ligand 2 or CD273, GenBank accession #NM_025239) and an engineered T-cell receptor (TCR) activator.

Polyclonal Apolipoprotein L2 Antibody
APR05494G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Apolipoprotein L2 . This antibody is tested and proven to work in the following applications:

Polyclonal PIWI-L2 Antibody
APR17843G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PIWI-L2 . This antibody is tested and proven to work in the following applications:

Polyclonal PIWI-L2 Antibody
APR17844G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PIWI-L2 . This antibody is tested and proven to work in the following applications:

PD-ECGF Polyclonal Antibody
ABP53145-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of PD-ECGF from Human. This PD-ECGF antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PD-ECGF

PD-ECGF Polyclonal Antibody
ABP53145-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of PD-ECGF from Human. This PD-ECGF antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PD-ECGF

PD-ECGF Polyclonal Antibody
ABP53145-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of PD-ECGF from Human. This PD-ECGF antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human PD-ECGF

PD-ECGF Polyclonal Antibody
ES4144-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against PD-ECGF from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

PD-ECGF Polyclonal Antibody
ES4144-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against PD-ECGF from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

PD-ECGF Polyclonal Antibody
41799-100ul 100ul
EUR 302.4

PD-ECGF Polyclonal Antibody
41799-50ul 50ul
EUR 224.4

PD-1 Polyclonal Antibody
27584-100ul 100ul
EUR 302.4

PD-1 Polyclonal Antibody
27584-50ul 50ul
EUR 224.4

Polyclonal PD-1 Antibody
APR06440G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PD-1 . This antibody is tested and proven to work in the following applications:

Polyclonal PD-1 Antibody
APR06441G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human PD-1 . This antibody is tested and proven to work in the following applications:

Recombinant Mouse PD-L2/B7-DC/CD273 (C-Fc)
CJ99-10ug 10ug
EUR 120
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Mouse PD-L2/B7-DC/CD273 (C-Fc)
CJ99-1mg 1mg
EUR 814.8
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Mouse PD-L2/B7-DC/CD273 (C-Fc)
CJ99-500ug 500ug
EUR 589.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Mouse PD-L2/B7-DC/CD273 (C-Fc)
CJ99-50ug 50ug
EUR 230.4
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Mouse Anti-Human CD273 (PD-L2), FITC Conjugated mAb
CM032-100T 100T
EUR 242.4

Mouse Anti-Human CD273 (PD-L2), FITC Conjugated mAb
CM032-25T 25T
EUR 181.2

Mouse Anti-Human CD273 (PD-L2), PE Conjugated mAb
CM033-100T 100T
EUR 494.4

Mouse Anti-Human CD273 (PD-L2), PE Conjugated mAb
CM033-25T 25T
EUR 242.4

Mouse Anti-Human CD273 (PD-L2), Biotin Conjugated mAb
CM034-100ug 100ug
EUR 416.4

Mouse Anti-Human CD273 (PD-L2), Biotin Conjugated mAb
CM034-25ug 25ug
EUR 224.4

Recombinant Human PD-L2/B7-DC/CD273 (C-mFC)
CW20-10ug 10ug
EUR 175.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human PD-L2/B7-DC/CD273 (C-mFC)
CW20-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human PD-L2/B7-DC/CD273 (C-mFC)
CW20-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human PD-L2/B7-DC/CD273 (C-mFC)
CW20-50ug 50ug
EUR 363.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human PD-L2/B7-DC/CD273 (C-6His)
CA09-10ug 10ug
EUR 242.4
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human PD-L2/B7-DC/CD273 (C-6His)
CA09-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human PD-L2/B7-DC/CD273 (C-6His)
CA09-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human PD-L2/B7-DC/CD273 (C-6His)
CA09-50ug 50ug
EUR 595.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human PD-L2 Protein (aa 1-219) [Fc]
VAng-Cr4038-100g 100 µg
EUR 1364.4
Description: Recombinant Human PD-L2 Protein (Met1-Pro219) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 49.3 kDa. (Accession ID: NP_079515.2)

Recombinant Human PD-L2 Protein (aa 1-219) [Fc]
VAng-Cr4038-200g 200 µg
EUR 2024.4
Description: Recombinant Human PD-L2 Protein (Met1-Pro219) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 49.3 kDa. (Accession ID: NP_079515.2)

Recombinant Cynomolgus PD-L2 Protein (aa 1-219) [Fc]
VAng-Cr4039-100g 100 µg
EUR 1364.4
Description: Recombinant Cynomolgus PD-L2 Protein (Met1-Pro219) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 49.6 kDa. (Accession ID: A4GW30)

Recombinant Cynomolgus PD-L2 Protein (aa 1-219) [Fc]
VAng-Cr4039-200g 200 µg
EUR 2024.4
Description: Recombinant Cynomolgus PD-L2 Protein (Met1-Pro219) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 49.6 kDa. (Accession ID: A4GW30)

Recombinant Rat PD-L2 Protein (aa 1-219) [Fc]
VAng-Cr4040-100g 100 µg
EUR 1364.4
Description: Recombinant Rat PD-L2 Protein (Met1-Arg219) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 49.2 kDa. (Accession ID: NP_001101052.2)

Recombinant Rat PD-L2 Protein (aa 1-219) [Fc]
VAng-Cr4040-200g 200 µg
EUR 2024.4
Description: Recombinant Rat PD-L2 Protein (Met1-Arg219) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 49.2 kDa. (Accession ID: NP_001101052.2)

Recombinant Mouse PD-L2 Protein (aa 1-219) [Fc]
VAng-Cr4041-100g 100 µg
EUR 1232.4
Description: Recombinant Mouse PD-L2 Protein (Met1-Arg219) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 49.5 kDa. (Accession ID: Q9WUL5)

Recombinant Mouse PD-L2 Protein (aa 1-219) [Fc]
VAng-Cr4041-200g 200 µg
EUR 2024.4
Description: Recombinant Mouse PD-L2 Protein (Met1-Arg219) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 49.5 kDa. (Accession ID: Q9WUL5)

Human CellExp? CD273 / B7-DC / PD-L2, human recombinant
7369-10 each
EUR 294

Human CellExp? CD273 / B7-DC / PD-L2, human recombinant
7369-50 each
EUR 836.4

Rat Anti-Mouse PD-L2 (B7-DC) Monoclonal antibody, clone TY25
CABT-L4293-1mg 1 mg
EUR 1076.4

Rat Anti-Mouse PD-L2 (B7-DC) Monoclonal antibody, clone TY25
CABT-L4293-5mg 5 mg
EUR 2886

PD-L1 Rabbit pAb
A11273-100ul 100 ul
EUR 369.6

PD-L1 Rabbit pAb
A11273-200ul 200 ul
EUR 550.8

PD-L1 Rabbit pAb
A11273-20ul 20 ul
EUR 219.6

PD-L2 Rabbit Polyclonal Antibody

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